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LEUCOVORIN 15 mg tablets 10 pc Calcium folinate Online now
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LEUCOVORIN Calcium folinate 10 pc
The active ingredient is: Calcium folinate 5 H2O1 tablet contains 19.06 mg calcium folinate 5 H2O equivalent to 15 mg folinic acid. — The other ingredients are: lactose monohydrate, cellulose powder, poly (ocarboxymethyl) starch sodium salt, corn starch partially sugar-coated, magnesium stearate
LEUCOVORIN Calcium folinate Application areas:
Leucovorin tablets are a detoxifying agent when using certain drugs to treat cancer and a means of preventing folic acid deficiency symptoms.
LEUCOVORIN Calcium folinate tablets are used for that
1. Prevention of symptoms of poisoning with (medium-) high-dose methotrexate therapy or with persistently high methotrexate serum levels (also with low-dose methotrexate therapies).
active ingredients
- 19.06 mg calcium folinate-5 water
-
excipients
- lactose-1 water
-
- cellulose powder
-
- Carboxymethyl Starch, Sodium
-
- Corn starch, pregelatinized
-
- magnesium stearate
-
indication
- The medicine is a detoxifying agent when using certain medicines to treat cancer and a means of preventing folic acid deficiency symptoms.
-
-
The medicinal product is used for
-
1. Prevention of symptoms of poisoning with (medium) high-dose methotrexate therapy or persistently high methotrexate serum levels (also with low-dose methotrexate therapies).
-
A notice:
- Persistently high methotrexate serum levels are to be expected in particular in the case of pleural effusions, ascites, renal insufficiency and insufficient fluid intake during methotrexate therapy.
-
-
-
- 2. Treatment of symptoms of intoxication from methotrexate therapy that can be attributed to tetrahydrofolic acid deficiency.
-
-
3. Treatment of folic acid deficiencies of various causes that cannot be remedied by dietary measures.
-
Hints:
- With this treatment, a vitamin B12 deficiency should be excluded in the differential diagnosis.
-
- In contrast to the areas of application mentioned under 1. and 2., the use of folic acid is sufficient here.
-
-
-
-
dosage
- Always take this medicine exactly as described or as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure.
-
- The preventive use of previous methotrexate use in cancer therapy is reserved for physicians who have sufficient experience in high-dose methotrexate therapy.
-
-
Unless otherwise prescribed by the doctor, the usual dose is:
-
1) in the prevention of symptoms of intoxication caused by tetrahydrofolic acid deficiency in methotrexate therapy (calcium folinate rescue):
-
From a methotrexate dosage of about 100 mg m 2 body surface area (BSA), this treatment must be followed by the administration of calcium folinate. There are no uniform recommendations for the dosage and type of application of calcium folinate as an antidote in high-dose methotrexate shock therapy, so the following dosage recommendations are given as examples:
-
-
Calcium folinate rescue after methotrexate (MTX) therapy:
-
MTX serum level 24 – 30 h: 1 x 10 -8 mol l to < 1.5 x 10 -6 mol l
-
Calcium folinate dose: 10 – 15 mg m 2 BSA every 6 hours
-
- Duration: 48 hours
-
-
-
MTX serum level 24 – 30 hours: 1.5 x 10 -6 mol l to 5 x 10 -6 mol l
-
Calcium folinate dose: 30 mg m 2 BSA every 6 h
-
-
Duration: until the plasma level is < 5 x 10 -8 mol l
-
-
-
MTX serum level 24 – 30 hours: > 5 x 10 -6 mol
LEUCOVORIN Calcium folinate Application areas:
Leucovorin tablets are a detoxifying agent when using certain drugs to treat cancer and a means of preventing folic acid deficiency symptoms.
LEUCOVORIN Calcium folinate tablets are used for that
1. Prevention of symptoms of poisoning with (medium-) high-dose methotrexate therapy or with persistently high methotrexate serum levels (also with low-dose methotrexate therapies).
active ingredients
- 19.06 mg calcium folinate-5 water
-
excipients
- lactose-1 water
-
- cellulose powder
-
- Carboxymethyl Starch, Sodium
-
- Corn starch, pregelatinized
-
- magnesium stearate
-
indication
- The medicine is a detoxifying agent when using certain medicines to treat cancer and a means of preventing folic acid deficiency symptoms.
-
-
The medicinal product is used for
-
1. Prevention of symptoms of poisoning with (medium) high-dose methotrexate therapy or persistently high methotrexate serum levels (also with low-dose methotrexate therapies).
-
A notice:
- Persistently high methotrexate serum levels are to be expected in particular in the case of pleural effusions, ascites, renal insufficiency and insufficient fluid intake during methotrexate therapy.
-
-
-
- 2. Treatment of symptoms of intoxication from methotrexate therapy that can be attributed to tetrahydrofolic acid deficiency.
-
-
3. Treatment of folic acid deficiencies of various causes that cannot be remedied by dietary measures.
-
Hints:
- With this treatment, a vitamin B12 deficiency should be excluded in the differential diagnosis.
-
- In contrast to the areas of application mentioned under 1. and 2., the use of folic acid is sufficient here.
-
-
-
-
dosage
- Always take this medicine exactly as described or as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure.
-
- The preventive use of previous methotrexate use in cancer therapy is reserved for physicians who have sufficient experience in high-dose methotrexate therapy.
-
-
Unless otherwise prescribed by the doctor, the usual dose is:
-
1) in the prevention of symptoms of intoxication caused by tetrahydrofolic acid deficiency in methotrexate therapy (calcium folinate rescue):
-
From a methotrexate dosage of about 100 mg m 2 body surface area (BSA), this treatment must be followed by the administration of calcium folinate. There are no uniform recommendations for the dosage and type of application of calcium folinate as an antidote in high-dose methotrexate shock therapy, so the following dosage recommendations are given as examples:
-
-
Calcium folinate rescue after methotrexate (MTX) therapy:
-
MTX serum level 24 – 30 h: 1 x 10 -8 mol l to < 1.5 x 10 -6 mol l
-
Calcium folinate dose: 10 – 15 mg m 2 BSA every 6 hours
-
- Duration: 48 hours
-
-
-
MTX serum level 24 – 30 hours: 1.5 x 10 -6 mol l to 5 x 10 -6 mol l
-
Calcium folinate dose: 30 mg m 2 BSA every 6 h
-
-
Duration: until the plasma level is < 5 x 10 -8 mol l
-
-
-
MTX serum level 24 – 30 hours: > 5 x 10 -6 mol
Leucovorin tablets are a detoxifying agent when using certain drugs to treat cancer and a means of preventing folic acid deficiency symptoms.
LEUCOVORIN Calcium folinate tablets are used for that
1. Prevention of symptoms of poisoning with (medium-) high-dose methotrexate therapy or with persistently high methotrexate serum levels (also with low-dose methotrexate therapies).
active ingredients
- 19.06 mg calcium folinate-5 water
-
excipients
- lactose-1 water
-
- cellulose powder
-
- Carboxymethyl Starch, Sodium
-
- Corn starch, pregelatinized
-
- magnesium stearate
-
indication
- The medicine is a detoxifying agent when using certain medicines to treat cancer and a means of preventing folic acid deficiency symptoms.
-
-
The medicinal product is used for
-
1. Prevention of symptoms of poisoning with (medium) high-dose methotrexate therapy or persistently high methotrexate serum levels (also with low-dose methotrexate therapies).
-
A notice:
- Persistently high methotrexate serum levels are to be expected in particular in the case of pleural effusions, ascites, renal insufficiency and insufficient fluid intake during methotrexate therapy.
-
-
-
- 2. Treatment of symptoms of intoxication from methotrexate therapy that can be attributed to tetrahydrofolic acid deficiency.
-
-
3. Treatment of folic acid deficiencies of various causes that cannot be remedied by dietary measures.
-
Hints:
- With this treatment, a vitamin B12 deficiency should be excluded in the differential diagnosis.
-
- In contrast to the areas of application mentioned under 1. and 2., the use of folic acid is sufficient here.
-
-
-
-
dosage
- Always take this medicine exactly as described or as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure.
-
- The preventive use of previous methotrexate use in cancer therapy is reserved for physicians who have sufficient experience in high-dose methotrexate therapy.
-
-
Unless otherwise prescribed by the doctor, the usual dose is:
-
1) in the prevention of symptoms of intoxication caused by tetrahydrofolic acid deficiency in methotrexate therapy (calcium folinate rescue):
-
From a methotrexate dosage of about 100 mg m 2 body surface area (BSA), this treatment must be followed by the administration of calcium folinate. There are no uniform recommendations for the dosage and type of application of calcium folinate as an antidote in high-dose methotrexate shock therapy, so the following dosage recommendations are given as examples:
-
-
Calcium folinate rescue after methotrexate (MTX) therapy:
-
MTX serum level 24 – 30 h: 1 x 10 -8 mol l to < 1.5 x 10 -6 mol l
-
Calcium folinate dose: 10 – 15 mg m 2 BSA every 6 hours
-
- Duration: 48 hours
-
-
-
MTX serum level 24 – 30 hours: 1.5 x 10 -6 mol l to 5 x 10 -6 mol l
-
Calcium folinate dose: 30 mg m 2 BSA every 6 h
-
-
Duration: until the plasma level is < 5 x 10 -8 mol l
-
-
-
MTX serum level 24 – 30 hours: > 5 x 10 -6 mol
- 19.06 mg calcium folinate-5 water
- lactose-1 water
- cellulose powder
- Carboxymethyl Starch, Sodium
- Corn starch, pregelatinized
- magnesium stearate
- The medicine is a detoxifying agent when using certain medicines to treat cancer and a means of preventing folic acid deficiency symptoms.
- The medicinal product is used for
-
1. Prevention of symptoms of poisoning with (medium) high-dose methotrexate therapy or persistently high methotrexate serum levels (also with low-dose methotrexate therapies).
-
A notice:
- Persistently high methotrexate serum levels are to be expected in particular in the case of pleural effusions, ascites, renal insufficiency and insufficient fluid intake during methotrexate therapy.
-
- 2. Treatment of symptoms of intoxication from methotrexate therapy that can be attributed to tetrahydrofolic acid deficiency.
- 3. Treatment of folic acid deficiencies of various causes that cannot be remedied by dietary measures.
-
Hints:
- With this treatment, a vitamin B12 deficiency should be excluded in the differential diagnosis.
- In contrast to the areas of application mentioned under 1. and 2., the use of folic acid is sufficient here.
-
-
-
- Always take this medicine exactly as described or as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure.
- The preventive use of previous methotrexate use in cancer therapy is reserved for physicians who have sufficient experience in high-dose methotrexate therapy.
- Unless otherwise prescribed by the doctor, the usual dose is:
-
1) in the prevention of symptoms of intoxication caused by tetrahydrofolic acid deficiency in methotrexate therapy (calcium folinate rescue):
-
From a methotrexate dosage of about 100 mg m 2 body surface area (BSA), this treatment must be followed by the administration of calcium folinate. There are no uniform recommendations for the dosage and type of application of calcium folinate as an antidote in high-dose methotrexate shock therapy, so the following dosage recommendations are given as examples:
- Calcium folinate rescue after methotrexate (MTX) therapy:
-
MTX serum level 24 – 30 h: 1 x 10 -8 mol l to < 1.5 x 10 -6 mol l
-
Calcium folinate dose: 10 – 15 mg m 2 BSA every 6 hours
- Duration: 48 hours
-
MTX serum level 24 – 30 hours: 1.5 x 10 -6 mol l to 5 x 10 -6 mol l
-
Calcium folinate dose: 30 mg m 2 BSA every 6 h
- Duration: until the plasma level is < 5 x 10 -8 mol l
-
MTX serum level 24 – 30 hours: > 5 x 10 -6 mol
-
Calcium folinate dose: 30 mg m 2 BSA every 6 h
-
Calcium folinate dose: 10 – 15 mg m 2 BSA every 6 hours
-
From a methotrexate dosage of about 100 mg m 2 body surface area (BSA), this treatment must be followed by the administration of calcium folinate. There are no uniform recommendations for the dosage and type of application of calcium folinate as an antidote in high-dose methotrexate shock therapy, so the following dosage recommendations are given as examples:
dosage
- Always take this medicine exactly as described or as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure.
-
-
- With this treatment, a vitamin B12 deficiency should be excluded in the differential diagnosis.
- Persistently high methotrexate serum levels are to be expected in particular in the case of pleural effusions, ascites, renal insufficiency and insufficient fluid intake during methotrexate therapy.
-
A notice:
indication
excipients